Atripla is a prescription drug that is used to treat HIV patients who are 12 years and above and 40kgs or more. It is specifically meant for HIV-1 i.e. human immunodeficiency virus-1. It may be used in conjunction with other antiretroviral drugs or as a full treatment regimen. It is a combination of 3 HIV drugs namely Tenofovir disoproxil fumarate, Efavirenz, and Emtricitabine. These drugs inhibit transcriptase which is an enzyme that accelerates the multiplication of HIV virus thereby reducing the viral count.
This drug can cause some life-threatening reactions in the human body. For instance, it causes lactic acidosis which is the accumulation of lactic acid in the blood which can lead to the complications in the liver. In case of the following side effects, the patient should contact a doctor immediately:
- Irregular heartbeat
- Abnormal muscle pain
- General tiredness
- Nausea, vomiting, loss of appetite, and stomach pain
- Breathing difficulty
- Extremely cold feet and hands
- Dark urine
- Skin yellowing
- Bowel movements and light colored stool
Some patients experience liver problems while taking the drug especially those who have a history of Hepatitis B and C. That is why liver tests are taken before the drug is administered. Anyone with chronic Hepatitis B infection cannot take the medicine because it will only worsen the situation.
For the drug to be prescribed, the patient must not have a history of virological failure on previous antiretroviral treatment and must not harbor virus strains with mutations that confer resistance to the components of this drug.
Atripla 600mg is known to react with particular drugs like those used in the treatment of HBV and other HIV medicines. It is recommended to maintain consistent appointments with a doctor when undergoing HIV therapy.
Composition and appearance:
Every tablet has tenofovir disoproxil (245 mg), efavirenz (600mg), and emtricitabine (200mg). It also contains 23.6mg of sodium. Basically, the pharmaceutical capsule is pink in color, film-coated, and measures 20 mm by 10.4 mm. One side of the pharmaceutical drug is plain while the other is debossed with ‘123’.
Dosage of the Atripla 600 mg tabs and administration guidelines:
One tablet per day is the recommended dose. In case of a missed dose, the tablet should be taken as soon as possible within 12 hours and the dosing schedule should continue as normal. But when a dose is missed by more than 12 hours, then there is no need to take the missed tablet. Another capsule must be ingested if a patient vomits within one hour of taking the drug. If vomiting happens more than one hour after the dose, there is no need to consume another tablet. The HIV drug is supposed to be taken when the stomach is empty because food may encourage efavirenz exposure and cause more complication. Taking Comprar Atripla 600 mg on an empty stomach minimizes tenofovir exposure by 30%. Furthermore, it is advisable to take the tablet before bedtime in order to enhance the tolerability of efavirenz.
If treatment is discontinued, it is imperative to consult a doctor to know the way forward. For patients who weigh 50kgs and above, they might need an extra 200mg per day if the Atripla is being taken together with rifampicin.
The medicine is not a cure for HIV but they help patients prolong their lives. Comprar Atripla 600 mg also minimizes the risk of transmitting HIV virus to other people.